Screening Mutations of MYBPC3 in 114 Unrelated Patients with Hypertrophic Cardiomyopathy by Targeted Capture and Next-generation Sequencing

Hypertrophic cardiomyopathy (HCM) is a major cause of sudden cardiac death. Mutations in the MYBPC3 gene represent the cause of HCM in ~35% of patients with HCM. However, genetic testing in clinic setting has been limited due to the cost and relatively time-consuming by Sanger sequencing. Here, we d...

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Detalles Bibliográficos
Autores principales: Liu, Xuxia, Jiang, Tengyong, Piao, Chunmei, Li, Xiaoyan, Guo, Jun, Zheng, Shuai, Zhang, Xiaoping, Cai, Tao, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473690/
https://www.ncbi.nlm.nih.gov/pubmed/26090888
http://dx.doi.org/10.1038/srep11411

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