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Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients
BACKGROUND: Epithelial-to-mesenchymal transition (EMT), which involves changes in cellular morphology of highly polarized epithelial cells and the gain of mesenchymal cell phenotype with migratory and invasive capacities, is implicated in smoking-related chronic obstructive pulmonary disease (COPD)....
Autores principales: | Nishioka, Michiyoshi, Venkatesan, Narayanan, Dessalle, Kevin, Mogas, Andrea, Kyoh, Shigenori, Lin, Ting-Yu, Nair, Parameswaran, Baglole, Carolyn J., Eidelman, David H., Ludwig, Mara S., Hamid, Qutayba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473826/ https://www.ncbi.nlm.nih.gov/pubmed/26081431 http://dx.doi.org/10.1186/s12931-015-0232-4 |
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