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Particulate cytoplasmic structures with high concentration of ubiquitin-proteasome accumulate in myeloid neoplasms

BACKGROUND: Increased plasma levels of proteasome have been associated with various neoplasms, especially myeloid malignancies. Little is known of the cellular origin and release mechanisms of such proteasome. We recently identified and characterized a novel particulate cytoplasmic structure (PaCS)...

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Detalles Bibliográficos
Autores principales: Pecci, Alessandro, Necchi, Vittorio, Barozzi, Serena, Vitali, Agostina, Boveri, Emanuela, Elena, Chiara, Bernasconi, Paolo, Noris, Patrizia, Solcia, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473848/
https://www.ncbi.nlm.nih.gov/pubmed/26081257
http://dx.doi.org/10.1186/s13045-015-0169-6