RTKN2 Induces NF-KappaB Dependent Resistance to Intrinsic Apoptosis in HEK Cells and Regulates BCL-2 Genes in Human CD4(+) Lymphocytes

The gene for Rhotekin 2 (RTKN2) was originally identified in a promyelocytic cell line resistant to oxysterol-induced apoptosis. It is differentially expressed in freshly isolated CD4(+) T-cells compared with other hematopoietic cells and is down-regulated following activation of the T-cell receptor...

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Detalles Bibliográficos
Autores principales: Collier, Fiona M, Loving, Andrea, Baker, Adele J, McLeod, Janet, Walder, Ken, Kirkland, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474337/
https://www.ncbi.nlm.nih.gov/pubmed/26124677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474337/
https://www.ncbi.nlm.nih.gov/pubmed/26124677

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