Tumour necrosis factor allele variants and their association with the occurrence and severity of malaria in African children: a longitudinal study

BACKGROUND: Tumour necrosis factor (TNF) is central to the immune response to Plasmodium infection. Its plasma concentration is influenced by allele variants in the promoter region of TNF. The study’s objectives were to assess TNF allele variants (TNF(−1031), TNF(−308)): (1) modulation of malaria ra...

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Detalles Bibliográficos
Autores principales: Gichohi-Wainaina, Wanjiku N, Melse-Boonstra, Alida, Feskens, Edith J, Demir, Ayse Y, Veenemans, Jacobien, Verhoef, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474355/
https://www.ncbi.nlm.nih.gov/pubmed/26088606
http://dx.doi.org/10.1186/s12936-015-0767-3

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