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Pathway-Dependent Effectiveness of Network Algorithms for Gene Prioritization
A network-based approach has proven useful for the identification of novel genes associated with complex phenotypes, including human diseases. Because network-based gene prioritization algorithms are based on propagating information of known phenotype-associated genes through networks, the pathway s...
Autores principales: | Shim, Jung Eun, Hwang, Sohyun, Lee, Insuk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474432/ https://www.ncbi.nlm.nih.gov/pubmed/26091506 http://dx.doi.org/10.1371/journal.pone.0130589 |
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