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Overexpression of the Large-Conductance, Ca(2+)-Activated K(+) (BK) Channel Shortens Action Potential Duration in HL-1 Cardiomyocytes
Long QT syndrome is characterized by a prolongation of the interval between the Q wave and the T wave on the electrocardiogram. This abnormality reflects a prolongation of the ventricular action potential caused by a number of genetic mutations or a variety of drugs. Since effective treatments are u...
Autores principales: | Stimers, Joseph R., Song, Li, Rusch, Nancy J., Rhee, Sung W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474436/ https://www.ncbi.nlm.nih.gov/pubmed/26091273 http://dx.doi.org/10.1371/journal.pone.0130588 |
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