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Ionizing radiation-induced foci persistence screen to discover enhancers of accelerated senescence

Much like replicative senescence, the irreversible cell-cycle arrest induced by eroded telomeres, accelerated senescence occurs when replicative cells suffer irreparable DNA double-strand breaks (DSBs). Along with apoptosis and necrosis, senescence is a desirable outcome in cancer treatment with ion...

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Detalles Bibliográficos
Autores principales:	Labay, Edwardine, Efimova, Elena V, Quarshie, Benjamin K, Golden, Daniel W, Weichselbaum, Ralph R, Kron, Stephen J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474479/ https://www.ncbi.nlm.nih.gov/pubmed/26097382 http://dx.doi.org/10.2147/IJHTS.S17076

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