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Comprehensive genome-wide transcription factor analysis reveals that a combination of high affinity and low affinity DNA binding is needed for human gene regulation

BACKGROUND: High-throughput in vivo protein-DNA interaction experiments are currently widely used in gene regulation studies. Hitherto, comprehensive data analysis remains a challenge and for that reason most computational methods only consider the top few hundred or thousand strongest protein bindi...

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Detalles Bibliográficos
Autores principales:	Wang, Junbai, Malecka, Agnieszka, Trøen, Gunhild, Delabie, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474539/ https://www.ncbi.nlm.nih.gov/pubmed/26099425 http://dx.doi.org/10.1186/1471-2164-16-S7-S12

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