Conditional U1 Gene Silencing in Toxoplasma gondii

The functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy based on U1 snRNP-mediated gene silencing. U1 snRNP is critical in pre-mRNA splicing by defini...

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Detalles Bibliográficos
Autores principales: Pieperhoff, Manuela S., Pall, Gurman S., Jiménez-Ruiz, Elena, Das, Sujaan, Melatti, Carmen, Gow, Matthew, Wong, Eleanor H., Heng, Joanne, Müller, Sylke, Blackman, Michael J., Meissner, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474610/
https://www.ncbi.nlm.nih.gov/pubmed/26090798
http://dx.doi.org/10.1371/journal.pone.0130356

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