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FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling

Most cartilaginous tumors are formed during skeletal development in locations adjacent to growth plates, suggesting that they arise from disordered endochondral bone growth. Fibroblast growth factor receptor (FGFR)3 signaling plays essential roles in this process; however, the role of FGFR3 in carti...

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Detalles Bibliográficos
Autores principales:	Zhou, Siru, Xie, Yangli, Tang, Junzhou, Huang, Junlan, Huang, Qizhao, Xu, Wei, Wang, Zuqiang, Luo, Fengtao, Wang, Quan, Chen, Hangang, Du, Xiaolan, Shen, Yue, Chen, Di, Chen, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474636/ https://www.ncbi.nlm.nih.gov/pubmed/26091072 http://dx.doi.org/10.1371/journal.pgen.1005214

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