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Contrasting Effects of Two Lipid Cofactors of Prion Replication on the Conformation of the Prion Protein

Recent studies introduced two experimental protocols for converting full-length recombinant prion protein (rPrP) purified from E.coli into the infectious prion state (PrP(Sc)) with high infectivity titers. Both protocols employed protein misfolding cyclic amplification (PMCA) for generating PrP(Sc)...

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Detalles Bibliográficos
Autores principales:	Srivastava, Saurabh, Baskakov, Ilia V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474664/ https://www.ncbi.nlm.nih.gov/pubmed/26090881 http://dx.doi.org/10.1371/journal.pone.0130283

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