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Naja naja oxiana Cobra Venom Cytotoxins CTI and CTII Disrupt Mitochondrial Membrane Integrity: Implications for Basic Three-Fingered Cytotoxins

Cobra venom cytotoxins are basic three-fingered, amphipathic, non-enzymatic proteins that constitute a major fraction of cobra venom. While cytotoxins cause mitochondrial dysfunction in different cell types, the mechanisms by which cytotoxins bind to mitochondria remain unknown. We analyzed the abil...

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Detalles Bibliográficos
Autores principales: Gasanov, Sardar E., Shrivastava, Indira H., Israilov, Firuz S., Kim, Aleksandr A., Rylova, Kamila A., Zhang, Boris, Dagda, Ruben K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474699/
https://www.ncbi.nlm.nih.gov/pubmed/26091109
http://dx.doi.org/10.1371/journal.pone.0129248