Novel ENU-Induced Mutation in Tbx6 Causes Dominant Spondylocostal Dysostosis-Like Vertebral Malformations in the Rat

Congenital vertebral malformations caused by embryonic segmentation defects are relatively common in humans and domestic animals. Although reverse genetics approaches in mice have provided information on the molecular mechanisms of embryonic somite segmentation, hypothesis-driven approaches cannot a...

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Detalles Bibliográficos
Autores principales: Abe, Koichiro, Takamatsu, Nobuhiko, Ishikawa, Kumiko, Tsurumi, Toshiko, Tanimoto, Sho, Sakurai, Yukina, Lisse, Thomas, Imai, Kenji, Serikawa, Tadao, Mashimo, Tomoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474719/
https://www.ncbi.nlm.nih.gov/pubmed/26090680
http://dx.doi.org/10.1371/journal.pone.0130231

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