HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-κB Pathway

We recently reported that the human immunodeficiency virus type-1 (HIV-1) Tat protein induced the expression of programmed death ligand-1 (PD-L1) on dendritic cells (DCs) through a TLR4 pathway. However, the underlying mechanisms by which HIV-1 Tat protein induces the abnormal hyper-activation of th...

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Detalles Bibliográficos
Autores principales: Ben Haij, Nawal, Planès, Rémi, Leghmari, Kaoutar, Serrero, Manutea, Delobel, Pierre, Izopet, Jacques, BenMohamed, Lbachir, Bahraoui, Elmostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474861/
https://www.ncbi.nlm.nih.gov/pubmed/26090662
http://dx.doi.org/10.1371/journal.pone.0129425

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