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Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells

BACKGROUND: CD8(+) T-cells are located in the small airways of COPD patients and may contribute to pathophysiology. CD8(+) cells express the chemokine receptor, CXCR3 that binds CXCL9, CXCL10 and CXCL11, which are elevated in the airways of COPD patients. These chemokines are released from airway ep...

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Detalles Bibliográficos
Autores principales:	Fenwick, Peter S., Macedo, Patricia, Kilty, Iain C., Barnes, Peter J., Donnelly, Louise E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474874/ https://www.ncbi.nlm.nih.gov/pubmed/26090665 http://dx.doi.org/10.1371/journal.pone.0128757

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