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Constitutive Activity in an Ancestral Form of Abl Tyrosine Kinase

The c-abl proto-oncogene encodes a nonreceptor tyrosine kinase that is found in all metazoans, and is ubiquitously expressed in mammalian tissues. The Abl tyrosine kinase plays important roles in the regulation of mammalian cell physiology. Abl-like kinases have been identified in the genomes of uni...

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Detalles Bibliográficos
Autores principales:	Aleem, Saadat U., Craddock, Barbara P., Miller, W. Todd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474922/ https://www.ncbi.nlm.nih.gov/pubmed/26090675 http://dx.doi.org/10.1371/journal.pone.0131062

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