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Invasive Surgery Impairs the Regulatory Function of Human CD56(bright) Natural Killer Cells in Response to Staphylococcus aureus. Suppression of Interferon-γ Synthesis
Major surgery increases the risk for infectious complications due to the development of immunosuppression. CD56(bright) NK cells play a key role in the defense against bacterial infections through the release of Interferon (IFN) γ upon stimulation with monocyte-derived Interleukin (IL) 12. We invest...
Autores principales: | Reinhardt, Renate, Pohlmann, Stephanie, Kleinertz, Holger, Hepner-Schefczyk, Monika, Paul, Andreas, Flohé, Stefanie B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474941/ https://www.ncbi.nlm.nih.gov/pubmed/26090673 http://dx.doi.org/10.1371/journal.pone.0130155 |
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