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Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR(-/-) Mice on Western Type Diet

OBJECTIVE: To investigate therapeutic effects of annexin A1 (anxA1) on atherogenesis in LDLR(-/-) mice. METHODS: Human recombinant annexin A1 (hr-anxA1) was produced by a prokaryotic expression system, purified and analysed on phosphatidylserine (PS) binding and formyl peptide receptor (FPR) activat...

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Detalles Bibliográficos
Autores principales:	Kusters, Dennis H. M., Chatrou, Martijn L., Willems, Brecht A. G., De Saint-Hubert, Marijke, Bauwens, Matthias, van der Vorst, Emiel, Bena, Stefania, Biessen, Erik A. L., Perretti, Mauro, Schurgers, Leon J., Reutelingsperger, Chris P. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475013/ https://www.ncbi.nlm.nih.gov/pubmed/26090792 http://dx.doi.org/10.1371/journal.pone.0130484

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