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Impacts of Chromatin States and Long-Range Genomic Segments on Aging and DNA Methylation

Understanding the fundamental dynamics of epigenome variation during normal aging is critical for elucidating key epigenetic alterations that affect development, cell differentiation and diseases. Advances in the field of aging and DNA methylation strongly support the aging epigenetic drift model. A...

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Detalles Bibliográficos
Autores principales: Sun, Dan, Yi, Soojin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475080/
https://www.ncbi.nlm.nih.gov/pubmed/26091484
http://dx.doi.org/10.1371/journal.pone.0128517