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Impacts of Chromatin States and Long-Range Genomic Segments on Aging and DNA Methylation
Understanding the fundamental dynamics of epigenome variation during normal aging is critical for elucidating key epigenetic alterations that affect development, cell differentiation and diseases. Advances in the field of aging and DNA methylation strongly support the aging epigenetic drift model. A...
Autores principales: | Sun, Dan, Yi, Soojin V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475080/ https://www.ncbi.nlm.nih.gov/pubmed/26091484 http://dx.doi.org/10.1371/journal.pone.0128517 |
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