Cargando…

High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice

BACKGROUND: DPP-4 inhibitors reportedly exert effects on both alpha and beta cells, and promote the proliferation and survival of beta cells. We investigated the effects of anagliptin on structurally-impaired islets of Langerhans in streptozotocin (STZ)-treated mice, fed either a normal or a high-fa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shinjo, Takanori, Nakatsu, Yusuke, Iwashita, Misaki, Sano, Tomomi, Sakoda, Hideyuki, Ishihara, Hisamitsu, Kushiyama, Akifumi, Fujishiro, Midori, Nishimura, Fusanori, Asano, Tomoichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475295/ https://www.ncbi.nlm.nih.gov/pubmed/26097511 http://dx.doi.org/10.1186/s13098-015-0047-y

Ejemplares similares

Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice
por: Iwashita, Misaki, et al.
Publicado: (2013)

Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice
por: Inoue, Masa-Ki, et al.
Publicado: (2019)

Impact of Plasma Xanthine Oxidoreductase Activity on the Mechanisms of Distal Symmetric Polyneuropathy Development in Patients with Type 2 Diabetes
por: Fujishiro, Midori, et al.
Publicado: (2021)

Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity
por: Yamamotoya, Takeshi, et al.
Publicado: (2017)

Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines
por: Kanna, Machi, et al.
Publicado: (2023)

Pathological Role of Pin1 in the Development of DSS-Induced Colitis
por: Matsunaga, Yasuka, et al.
Publicado: (2021)

Reduced SHARPIN and LUBAC Formation May Contribute to CCl(4)- or Acetaminophen-Induced Liver Cirrhosis in Mice
por: Yamamotoya, Takeshi, et al.
Publicado: (2017)

Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages
por: Yamazaki, Hiroki, et al.
Publicado: (2018)

Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications
por: Okubo, Hirofumi, et al.
Publicado: (2018)

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis
por: Matsunaga, Yasuka, et al.
Publicado: (2015)

Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus
por: Qiang, Shirong, et al.
Publicado: (2015)

Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis
por: Kushiyama, Akifumi, et al.
Publicado: (2016)

Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations
por: Nakatsu, Yusuke, et al.
Publicado: (2016)

Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells
por: Hasei, Shun, et al.
Publicado: (2021)

Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice
por: Okubo, Hirofumi, et al.
Publicado: (2016)

Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases
por: Yamamotoya, Takeshi, et al.
Publicado: (2022)

Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure
por: Sano, Tomomi, et al.
Publicado: (2019)

Pin1 Plays Essential Roles in NASH Development by Modulating Multiple Target Proteins
por: Inoue, Masa-Ki, et al.
Publicado: (2019)

Anti-inflammatory effects of miRNA-146a induced in adipose and periodontal tissues
por: Sanada, Taiki, et al.
Publicado: (2020)

Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines
por: Kanaoka, Ryuhei, et al.
Publicado: (2015)

Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells
por: Akasaka, Yasuyuki, et al.
Publicado: (2023)

Adipose-specific C-C motif chemokine ligand (CCL) 19 overexpression drives the mice to both insulin resistance and weight gain
por: Hayashi, Masato, et al.
Publicado: (2021)

The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice
por: Nakatsu, Yusuke, et al.
Publicado: (2017)

Prolyl isomerase Pin1 binds to and stabilizes acetyl CoA carboxylase 1 protein, thereby supporting cancer cell proliferation
por: Ueda, Koji, et al.
Publicado: (2019)

The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model
por: Inoue, Masa-Ki, et al.
Publicado: (2018)

XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis
por: Nishimura, Yuki, et al.
Publicado: (2022)

Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice
por: Mizuno, Yu, et al.
Publicado: (2019)

SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth
por: Alshargabi, Rehab, et al.
Publicado: (2020)

A Case Report of Improved Palmoplantar Pustulosis following Periodontal Treatment and Possible Association with Diminished Systemic Subclinical Inflammation
por: Yamashita, Akiko, et al.
Publicado: (2021)

The Cells of the Islets of Langerhans
por: Da Silva Xavier, Gabriela
Publicado: (2018)

Gastrointestinal symptom prevalence depends on disease duration and gastrointestinal region in type 2 diabetes mellitus
por: Fujishiro, Midori, et al.
Publicado: (2017)

Estrogens counteract tributyltin-induced toxicity in the rat islets of Langerhans
por: Ghaemmaleki, Faezeh, et al.
Publicado: (2020)

Axon Guidance Molecules in the Islets of Langerhans
por: Waters, Bayley J., et al.
Publicado: (2022)

An Autonomous Cannabinoid System in Islets of Langerhans
por: Aseer, Kanikkai Raja, et al.
Publicado: (2021)

Effects of anagliptin on the stress induced accelerated senescence of human umbilical vein endothelial cells
por: Kang, Seon Mee, et al.
Publicado: (2021)

Islet Remodeling in Female Mice with Spontaneous Autoimmune and Streptozotocin-Induced Diabetes
por: Plesner, Annette, et al.
Publicado: (2014)

Microwell Scaffolds for the Extrahepatic Transplantation of Islets of Langerhans
por: Buitinga, Mijke, et al.
Publicado: (2013)

Purification of Islets of Langerhans from Porcine Pancreas
por: Graham, John
Publicado: (2002)

Geometric and topological characterization of the cytoarchitecture of islets of Langerhans
por: Aggarwal, Manu, et al.
Publicado: (2023)

Anagliptin alleviates lipopolysaccharide-induced inflammation, apoptosis and endothelial dysfunction of lung microvascular endothelial cells
por: Zhang, Jingli, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ad4rm7gd1a2mk5sdeg6keeglda