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Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay

Nonsense-mediated mRNA decay (NMD) is a post-transcriptional mechanism that targets aberrant transcripts and regulates the cellular RNA reservoir. Genetic modulation in vertebrates suggests that NMD is critical for cellular and tissue homeostasis, although the underlying mechanism remains elusive. H...

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Detalles Bibliográficos
Autores principales:	Li, Tangliang, Shi, Yue, Wang, Pei, Guachalla, Luis Miguel, Sun, Baofa, Joerss, Tjard, Chen, Yu-Sheng, Groth, Marco, Krueger, Anja, Platzer, Matthias, Yang, Yun-Gui, Rudolph, Karl Lenhard, Wang, Zhao-Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475398/ https://www.ncbi.nlm.nih.gov/pubmed/25770585 http://dx.doi.org/10.15252/embj.201489947

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