Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis

Psoriasis is a chronic inflammatory skin disease where the altered regulation in angiogenesis, inflammation, and proliferation of keratinocytes are the possible causes of the disease, and the transcription factor “hypoxia-inducible factor 1-alpha” (HIF-1α) is involved in the homeostasis of these thr...

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Autores principales: Torales-Cardeña, Azael, Martínez-Torres, Isaí, Rodríguez-Martínez, Sandra, Gómez-Chávez, Fernando, Cancino-Díaz, Juan C., Vázquez-Sánchez, Ernesto A., Cancino-Díaz, Mario E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475568/
https://www.ncbi.nlm.nih.gov/pubmed/26136626
http://dx.doi.org/10.1155/2015/607363
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author Torales-Cardeña, Azael
Martínez-Torres, Isaí
Rodríguez-Martínez, Sandra
Gómez-Chávez, Fernando
Cancino-Díaz, Juan C.
Vázquez-Sánchez, Ernesto A.
Cancino-Díaz, Mario E.
author_facet Torales-Cardeña, Azael
Martínez-Torres, Isaí
Rodríguez-Martínez, Sandra
Gómez-Chávez, Fernando
Cancino-Díaz, Juan C.
Vázquez-Sánchez, Ernesto A.
Cancino-Díaz, Mario E.
author_sort Torales-Cardeña, Azael
collection PubMed
description Psoriasis is a chronic inflammatory skin disease where the altered regulation in angiogenesis, inflammation, and proliferation of keratinocytes are the possible causes of the disease, and the transcription factor “hypoxia-inducible factor 1-alpha” (HIF-1α) is involved in the homeostasis of these three biological phenomena. In this review, the role of HIF-1α in the cross talk between the cytokines and cells of the immunological system involved in the pathogenesis of psoriasis is discussed.
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spelling pubmed-44755682015-07-01 Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis Torales-Cardeña, Azael Martínez-Torres, Isaí Rodríguez-Martínez, Sandra Gómez-Chávez, Fernando Cancino-Díaz, Juan C. Vázquez-Sánchez, Ernesto A. Cancino-Díaz, Mario E. Mediators Inflamm Review Article Psoriasis is a chronic inflammatory skin disease where the altered regulation in angiogenesis, inflammation, and proliferation of keratinocytes are the possible causes of the disease, and the transcription factor “hypoxia-inducible factor 1-alpha” (HIF-1α) is involved in the homeostasis of these three biological phenomena. In this review, the role of HIF-1α in the cross talk between the cytokines and cells of the immunological system involved in the pathogenesis of psoriasis is discussed. Hindawi Publishing Corporation 2015 2015-06-07 /pmc/articles/PMC4475568/ /pubmed/26136626 http://dx.doi.org/10.1155/2015/607363 Text en Copyright © 2015 Azael Torales-Cardeña et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Torales-Cardeña, Azael
Martínez-Torres, Isaí
Rodríguez-Martínez, Sandra
Gómez-Chávez, Fernando
Cancino-Díaz, Juan C.
Vázquez-Sánchez, Ernesto A.
Cancino-Díaz, Mario E.
Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis
title Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis
title_full Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis
title_fullStr Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis
title_full_unstemmed Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis
title_short Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis
title_sort cross talk between proliferative, angiogenic, and cellular mechanisms orchestred by hif-1α in psoriasis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475568/
https://www.ncbi.nlm.nih.gov/pubmed/26136626
http://dx.doi.org/10.1155/2015/607363
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