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Gabapentin prevents oxaliplatin-induced central sensitization in the dorsal horn neurons in rats
OBJECTIVE(S): The present study aims to study the alteration of glutamatergic transmission in the dorsal horn neurons and the effect of gabapentin on oxaliplatin-induced neuropathic pain in rats. MATERIALS AND METHODS: Oxaliplatin (5 mg/kg) or saline was administered to adult male Sprague-Dawley rat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475658/ https://www.ncbi.nlm.nih.gov/pubmed/26124936 |