Persistence of anti–chikungunya virus–specific antibodies in a cohort of patients followed from the acute phase of infection after the 2007 outbreak in Italy

Chikungunya is a mosquito-borne infection of humans, and its diffusion has increased worldwide. In 2007 an outbreak occurred in Italy. In this study, the antibody response of 133 patients followed up starting from the acute phase of infection was investigated. Antibody titres were periodically score...

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Autores principales: Pierro, A., Rossini, G., Gaibani, P., Finarelli, A.C., Moro, M.L., Landini, M.P., Sambri, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
New Microbes in Humans
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475829/
https://www.ncbi.nlm.nih.gov/pubmed/26106482
http://dx.doi.org/10.1016/j.nmni.2015.04.002
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author Pierro, A.
Rossini, G.
Gaibani, P.
Finarelli, A.C.
Moro, M.L.
Landini, M.P.
Sambri, V.
author_facet Pierro, A.
Rossini, G.
Gaibani, P.
Finarelli, A.C.
Moro, M.L.
Landini, M.P.
Sambri, V.
author_sort Pierro, A.
collection PubMed
description Chikungunya is a mosquito-borne infection of humans, and its diffusion has increased worldwide. In 2007 an outbreak occurred in Italy. In this study, the antibody response of 133 patients followed up starting from the acute phase of infection was investigated. Antibody titres were periodically scored up to 1 year since the infection: 82.7% of the IgM antibody disappeared within 12 months, and the IgG response lasted longer than 12 months. Nevertheless, the IgG mean titre was lower in 95.5% of patients at the end of follow-up, thus suggesting a decrease within a relatively short period.
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spelling pubmed-44758292015-06-23 Persistence of anti–chikungunya virus–specific antibodies in a cohort of patients followed from the acute phase of infection after the 2007 outbreak in Italy Pierro, A. Rossini, G. Gaibani, P. Finarelli, A.C. Moro, M.L. Landini, M.P. Sambri, V. New Microbes New Infect New Microbes in Humans Chikungunya is a mosquito-borne infection of humans, and its diffusion has increased worldwide. In 2007 an outbreak occurred in Italy. In this study, the antibody response of 133 patients followed up starting from the acute phase of infection was investigated. Antibody titres were periodically scored up to 1 year since the infection: 82.7% of the IgM antibody disappeared within 12 months, and the IgG response lasted longer than 12 months. Nevertheless, the IgG mean titre was lower in 95.5% of patients at the end of follow-up, thus suggesting a decrease within a relatively short period. Elsevier 2015-04-15 /pmc/articles/PMC4475829/ /pubmed/26106482 http://dx.doi.org/10.1016/j.nmni.2015.04.002 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle New Microbes in Humans
Pierro, A.
Rossini, G.
Gaibani, P.
Finarelli, A.C.
Moro, M.L.
Landini, M.P.
Sambri, V.
Persistence of anti–chikungunya virus–specific antibodies in a cohort of patients followed from the acute phase of infection after the 2007 outbreak in Italy
title Persistence of anti–chikungunya virus–specific antibodies in a cohort of patients followed from the acute phase of infection after the 2007 outbreak in Italy
title_full Persistence of anti–chikungunya virus–specific antibodies in a cohort of patients followed from the acute phase of infection after the 2007 outbreak in Italy
title_fullStr Persistence of anti–chikungunya virus–specific antibodies in a cohort of patients followed from the acute phase of infection after the 2007 outbreak in Italy
title_full_unstemmed Persistence of anti–chikungunya virus–specific antibodies in a cohort of patients followed from the acute phase of infection after the 2007 outbreak in Italy
title_short Persistence of anti–chikungunya virus–specific antibodies in a cohort of patients followed from the acute phase of infection after the 2007 outbreak in Italy
title_sort persistence of anti–chikungunya virus–specific antibodies in a cohort of patients followed from the acute phase of infection after the 2007 outbreak in italy
topic New Microbes in Humans
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475829/
https://www.ncbi.nlm.nih.gov/pubmed/26106482
http://dx.doi.org/10.1016/j.nmni.2015.04.002
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