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Aquaporin-4 antibody isoform binding specificities do not explain clinical variations in NMO

OBJECTIVE: To assess the clinical relevance of the differential binding of antibodies against the 2 main aquaporin-4 (AQP4) isoforms in neuromyelitis optica (NMO) patient sera using stably transfected human embryonic kidney cells. METHODS: Flow cytometry of human embryonic kidney cells stably transf...

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Detalles Bibliográficos
Autores principales: Kitley, Joanna, Woodhall, Mark, Leite, M. Isabel, Palace, Jackie, Vincent, Angela, Waters, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476052/
https://www.ncbi.nlm.nih.gov/pubmed/26140280
http://dx.doi.org/10.1212/NXI.0000000000000121