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Voltage-gated Na(+) Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling

Functional expression of voltage-gated Na(+) channels (VGSCs) has been demonstrated in multiple cancer cell types where channel activity induces invasive activity. The signaling mechanisms by which VGSCs promote oncogenesis remain poorly understood. We explored the signal transduction process critic...

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Detalles Bibliográficos
Autores principales:	House, Carrie D., Wang, Bi-Dar, Ceniccola, Kristin, Williams, Russell, Simaan, May, Olender, Jacqueline, Patel, Vyomesh, Baptista-Hon, Daniel T., Annunziata, Christina M., Silvio Gutkind, J., Hales, Tim G., Lee, Norman H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476109/ https://www.ncbi.nlm.nih.gov/pubmed/26096612 http://dx.doi.org/10.1038/srep11541

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