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Quantitative modeling of dose–response and drug combination based on pathway network
BACKGROUND: Quantitative description of dose–response of a drug for complex systems is essential for treatment of diseases and drug discovery. Given the growth of large-scale biological data obtained by multi-level assays, computational modeling has become an important approach to understand the mec...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476235/ https://www.ncbi.nlm.nih.gov/pubmed/26101547 http://dx.doi.org/10.1186/s13321-015-0066-6 |