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Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet

BACKGROUND: Oxidative stress underlies the etiopathogenesis of nonalcoholic fatty liver disease (NAFLD), obesity and cardiovascular disease (CVD). Heme Oxygenase-1 (HO-1) is a potent endogenous antioxidant gene that plays a key role in decreasing oxidative stress. Sirtuin1 (SIRT1) belongs to the fam...

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Detalles Bibliográficos
Autores principales:	Sodhi, Komal, Puri, Nitin, Favero, Gaia, Stevens, Sarah, Meadows, Charles, Abraham, Nader G., Rezzani, Rita, Ansinelli, Hayden, Lebovics, Edward, Shapiro, Joseph I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476565/ https://www.ncbi.nlm.nih.gov/pubmed/26098879 http://dx.doi.org/10.1371/journal.pone.0128648

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