Nanomicellar Formulation of Clotrimazole Improves Its Antitumor Action toward Human Breast Cancer Cells

BACKGROUND: Although demonstrated as a selective anticancer drug, the clinical use of clotrimazole (CTZ) is limited due to its low solubility in hydrophilic fluids. Thus, we prepared a water-soluble nanomicellar formulation of CTZ ((n)CTZ) and tested on the human breast cancer cell line MCF-7 biolog...

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Detalles Bibliográficos
Autores principales: Marcondes, Mariah C., Fernandes, Anne C. S., Itabaiana, Ivaldo, de Souza, Rodrigo O. M. A., Sola-Penna, Mauro, Zancan, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476588/
https://www.ncbi.nlm.nih.gov/pubmed/26098874
http://dx.doi.org/10.1371/journal.pone.0130555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476588/
https://www.ncbi.nlm.nih.gov/pubmed/26098874
http://dx.doi.org/10.1371/journal.pone.0130555

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