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N-Linked Glycans Are Assembled on Highly Reduced Dolichol Phosphate Carriers in the Hyperthermophilic Archaea Pyrococcus furiosus

In all three domains of life, N-glycosylation begins with the assembly of glycans on phosphorylated polyisoprenoid carriers. Like eukaryotes, archaea also utilize phosphorylated dolichol for this role, yet whereas the assembled oligosaccharide is transferred to target proteins from dolichol pyrophos...

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Detalles Bibliográficos
Autores principales: Chang, Michelle M., Imperiali, Barbara, Eichler, Jerry, Guan, Ziqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476749/
https://www.ncbi.nlm.nih.gov/pubmed/26098850
http://dx.doi.org/10.1371/journal.pone.0130482