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Bayesian Estimation of the Active Concentration and Affinity Constants Using Surface Plasmon Resonance Technology
Surface plasmon resonance (SPR) has previously been employed to measure the active concentration of analyte in addition to the kinetic rate constants in molecular binding reactions. Those approaches, however, have a few restrictions. In this work, a Bayesian approach is developed to determine both a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476803/ https://www.ncbi.nlm.nih.gov/pubmed/26098764 http://dx.doi.org/10.1371/journal.pone.0130812 |