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Efflux pump-deficient mutants as a platform to search for microbes that produce antibiotics
Pseudomonas putida DOT-T1E-18 is a strain deficient in the major antibiotic efflux pump (TtgABC) that exhibits an overall increased susceptibility to a wide range of drugs when compared with the wild-type strain. We used this strain as a platform to search for microbes able to produce antibiotics th...
Autores principales: | Molina-Santiago, Carlos, Udaondo, Zulema, Daddaoua, Abdelali, Roca, Amalia, Martín, Jesús, Pérez-Victoria, Ignacio, Reyes, Fernando, Ramos, Juan-Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476826/ https://www.ncbi.nlm.nih.gov/pubmed/26059350 http://dx.doi.org/10.1111/1751-7915.12295 |
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