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Second-line agents in myositis: 1-year factorial trial of additional immunosuppression in patients who have partially responded to steroids
Objective. Ciclosporin and MTX are used in idiopathic inflammatory myopathies (DM and PM) when patients incompletely respond to glucocorticoids. Their effectiveness is unproved in randomized controlled trials (RCTs). We evaluated their benefits in a placebo-controlled factorial RCT. Methods. A 56-we...
Autores principales: | Ibrahim, Fowzia, Choy, Ernest, Gordon, Patrick, Doré, Caroline J., Hakim, Alan, Kitas, George, Isenberg, David, Griffiths, Bridget, Lecky, Bryan, Chakravarty, Kuntal, Winer, John, Danko, Katalin, Cooper, Robert G., White-Alao, Beverley, Scott, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476843/ https://www.ncbi.nlm.nih.gov/pubmed/25433040 http://dx.doi.org/10.1093/rheumatology/keu442 |
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