Cargando…

Metagenomics: A new horizon in cancer research

Metagenomics has broadened the scope of targeting microbes responsible for inducing various types of cancers. About 16.1% of cancers are associated with microbial infection. Metagenomics is an equitable way of identifying and studying micro-organisms within their habitat. In cancer research, this ap...

Descripción completa

Detalles Bibliográficos
Autores principales: Banerjee, Joyita, Mishra, Neetu, Dhas, Yogita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477109/
https://www.ncbi.nlm.nih.gov/pubmed/26110115
http://dx.doi.org/10.1016/j.mgene.2015.05.005
_version_ 1782377695438438400
author Banerjee, Joyita
Mishra, Neetu
Dhas, Yogita
author_facet Banerjee, Joyita
Mishra, Neetu
Dhas, Yogita
author_sort Banerjee, Joyita
collection PubMed
description Metagenomics has broadened the scope of targeting microbes responsible for inducing various types of cancers. About 16.1% of cancers are associated with microbial infection. Metagenomics is an equitable way of identifying and studying micro-organisms within their habitat. In cancer research, this approach has revolutionized the way of identifying, analyzing and targeting the microbial diversity present in the tissue specimens of cancer patients. The genomic analyses of these micro-organisms through next generation sequencing techniques invariably facilitate in recognizing the microbial population in biopsies and their evolutionary relationships with each other. In this review an attempt has been made to generate current metagenomic view on cancer microbiota. Different types of micro-organisms have been found to be linked to various types of cancers, thus, contributing significantly in understanding the disease at molecular level.
format Online
Article
Text
id pubmed-4477109
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-44771092015-06-24 Metagenomics: A new horizon in cancer research Banerjee, Joyita Mishra, Neetu Dhas, Yogita Meta Gene Article Metagenomics has broadened the scope of targeting microbes responsible for inducing various types of cancers. About 16.1% of cancers are associated with microbial infection. Metagenomics is an equitable way of identifying and studying micro-organisms within their habitat. In cancer research, this approach has revolutionized the way of identifying, analyzing and targeting the microbial diversity present in the tissue specimens of cancer patients. The genomic analyses of these micro-organisms through next generation sequencing techniques invariably facilitate in recognizing the microbial population in biopsies and their evolutionary relationships with each other. In this review an attempt has been made to generate current metagenomic view on cancer microbiota. Different types of micro-organisms have been found to be linked to various types of cancers, thus, contributing significantly in understanding the disease at molecular level. Elsevier 2015-06-14 /pmc/articles/PMC4477109/ /pubmed/26110115 http://dx.doi.org/10.1016/j.mgene.2015.05.005 Text en © 2015 The Authors. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Banerjee, Joyita
Mishra, Neetu
Dhas, Yogita
Metagenomics: A new horizon in cancer research
title Metagenomics: A new horizon in cancer research
title_full Metagenomics: A new horizon in cancer research
title_fullStr Metagenomics: A new horizon in cancer research
title_full_unstemmed Metagenomics: A new horizon in cancer research
title_short Metagenomics: A new horizon in cancer research
title_sort metagenomics: a new horizon in cancer research
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477109/
https://www.ncbi.nlm.nih.gov/pubmed/26110115
http://dx.doi.org/10.1016/j.mgene.2015.05.005
work_keys_str_mv AT banerjeejoyita metagenomicsanewhorizonincancerresearch
AT mishraneetu metagenomicsanewhorizonincancerresearch
AT dhasyogita metagenomicsanewhorizonincancerresearch