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Metagenomics: A new horizon in cancer research
Metagenomics has broadened the scope of targeting microbes responsible for inducing various types of cancers. About 16.1% of cancers are associated with microbial infection. Metagenomics is an equitable way of identifying and studying micro-organisms within their habitat. In cancer research, this ap...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477109/ https://www.ncbi.nlm.nih.gov/pubmed/26110115 http://dx.doi.org/10.1016/j.mgene.2015.05.005 |
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author | Banerjee, Joyita Mishra, Neetu Dhas, Yogita |
author_facet | Banerjee, Joyita Mishra, Neetu Dhas, Yogita |
author_sort | Banerjee, Joyita |
collection | PubMed |
description | Metagenomics has broadened the scope of targeting microbes responsible for inducing various types of cancers. About 16.1% of cancers are associated with microbial infection. Metagenomics is an equitable way of identifying and studying micro-organisms within their habitat. In cancer research, this approach has revolutionized the way of identifying, analyzing and targeting the microbial diversity present in the tissue specimens of cancer patients. The genomic analyses of these micro-organisms through next generation sequencing techniques invariably facilitate in recognizing the microbial population in biopsies and their evolutionary relationships with each other. In this review an attempt has been made to generate current metagenomic view on cancer microbiota. Different types of micro-organisms have been found to be linked to various types of cancers, thus, contributing significantly in understanding the disease at molecular level. |
format | Online Article Text |
id | pubmed-4477109 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-44771092015-06-24 Metagenomics: A new horizon in cancer research Banerjee, Joyita Mishra, Neetu Dhas, Yogita Meta Gene Article Metagenomics has broadened the scope of targeting microbes responsible for inducing various types of cancers. About 16.1% of cancers are associated with microbial infection. Metagenomics is an equitable way of identifying and studying micro-organisms within their habitat. In cancer research, this approach has revolutionized the way of identifying, analyzing and targeting the microbial diversity present in the tissue specimens of cancer patients. The genomic analyses of these micro-organisms through next generation sequencing techniques invariably facilitate in recognizing the microbial population in biopsies and their evolutionary relationships with each other. In this review an attempt has been made to generate current metagenomic view on cancer microbiota. Different types of micro-organisms have been found to be linked to various types of cancers, thus, contributing significantly in understanding the disease at molecular level. Elsevier 2015-06-14 /pmc/articles/PMC4477109/ /pubmed/26110115 http://dx.doi.org/10.1016/j.mgene.2015.05.005 Text en © 2015 The Authors. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Banerjee, Joyita Mishra, Neetu Dhas, Yogita Metagenomics: A new horizon in cancer research |
title | Metagenomics: A new horizon in cancer research |
title_full | Metagenomics: A new horizon in cancer research |
title_fullStr | Metagenomics: A new horizon in cancer research |
title_full_unstemmed | Metagenomics: A new horizon in cancer research |
title_short | Metagenomics: A new horizon in cancer research |
title_sort | metagenomics: a new horizon in cancer research |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477109/ https://www.ncbi.nlm.nih.gov/pubmed/26110115 http://dx.doi.org/10.1016/j.mgene.2015.05.005 |
work_keys_str_mv | AT banerjeejoyita metagenomicsanewhorizonincancerresearch AT mishraneetu metagenomicsanewhorizonincancerresearch AT dhasyogita metagenomicsanewhorizonincancerresearch |