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Applications of hydrogen deuterium exchange (HDX) for the characterization of conformational dynamics in light-activated photoreceptors

Rational design of optogenetic tools is inherently linked to the understanding of photoreceptor function. Structural analysis of elements involved in signal integration in individual sensor domains provides an initial idea of their mode of operation, but understanding how local structural rearrangem...

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Detalles Bibliográficos
Autores principales: Lindner, Robert, Heintz, Udo, Winkler, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477167/
https://www.ncbi.nlm.nih.gov/pubmed/26157802
http://dx.doi.org/10.3389/fmolb.2015.00033