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Interplay between Intravitreal RvD1 and Local Endogenous Sirtuin-1 in the Protection from Endotoxin-Induced Uveitis in Rats
Rat endotoxin-induced uveitis (EIU) is a well-established model of human uveitis. In this model, intravitreal injection of resolvin D1 (RvD1, 10–100–1000 ng/kg) 1 hour after subcutaneous treatment of Sprague-Dawley rats with lipopolysaccharide (LPS, 200 μg/rat) significantly prevented the developmen...
Autores principales: | Rossi, S., Di Filippo, C., Gesualdo, C., Testa, F., Trotta, M. C., Maisto, R., Ferraro, B., Ferraraccio, F., Accardo, M., Simonelli, F., D'Amico, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477183/ https://www.ncbi.nlm.nih.gov/pubmed/26180376 http://dx.doi.org/10.1155/2015/126408 |
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