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Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer
Raman spectroscopy provides a unique biochemical fingerprint capable of identifying and characterizing the structure of molecules, cells, and tissues. In cervical cancer, it is acknowledged as a promising biochemical tool due to its ability to detect premalignancy and early malignancy stages. This r...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477184/ https://www.ncbi.nlm.nih.gov/pubmed/26180802 http://dx.doi.org/10.1155/2015/561242 |
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author | Ramos, Inês Raquel Martins Malkin, Alison Lyng, Fiona Mary |
author_facet | Ramos, Inês Raquel Martins Malkin, Alison Lyng, Fiona Mary |
author_sort | Ramos, Inês Raquel Martins |
collection | PubMed |
description | Raman spectroscopy provides a unique biochemical fingerprint capable of identifying and characterizing the structure of molecules, cells, and tissues. In cervical cancer, it is acknowledged as a promising biochemical tool due to its ability to detect premalignancy and early malignancy stages. This review summarizes the key research in the area and the evidence compiled is very encouraging for ongoing and further research. In addition to the diagnostic potential, promising results for HPV detection and monitoring treatment response suggest more than just a diagnosis prospective. A greater body of evidence is however necessary before Raman spectroscopy is fully validated for clinical use and larger comprehensive studies are required to fully establish the role of Raman spectroscopy in the molecular diagnostics of cervical cancer. |
format | Online Article Text |
id | pubmed-4477184 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-44771842015-07-15 Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer Ramos, Inês Raquel Martins Malkin, Alison Lyng, Fiona Mary Biomed Res Int Review Article Raman spectroscopy provides a unique biochemical fingerprint capable of identifying and characterizing the structure of molecules, cells, and tissues. In cervical cancer, it is acknowledged as a promising biochemical tool due to its ability to detect premalignancy and early malignancy stages. This review summarizes the key research in the area and the evidence compiled is very encouraging for ongoing and further research. In addition to the diagnostic potential, promising results for HPV detection and monitoring treatment response suggest more than just a diagnosis prospective. A greater body of evidence is however necessary before Raman spectroscopy is fully validated for clinical use and larger comprehensive studies are required to fully establish the role of Raman spectroscopy in the molecular diagnostics of cervical cancer. Hindawi Publishing Corporation 2015 2015-06-09 /pmc/articles/PMC4477184/ /pubmed/26180802 http://dx.doi.org/10.1155/2015/561242 Text en Copyright © 2015 Inês Raquel Martins Ramos et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Ramos, Inês Raquel Martins Malkin, Alison Lyng, Fiona Mary Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer |
title | Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer |
title_full | Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer |
title_fullStr | Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer |
title_full_unstemmed | Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer |
title_short | Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer |
title_sort | current advances in the application of raman spectroscopy for molecular diagnosis of cervical cancer |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477184/ https://www.ncbi.nlm.nih.gov/pubmed/26180802 http://dx.doi.org/10.1155/2015/561242 |
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