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Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer

Raman spectroscopy provides a unique biochemical fingerprint capable of identifying and characterizing the structure of molecules, cells, and tissues. In cervical cancer, it is acknowledged as a promising biochemical tool due to its ability to detect premalignancy and early malignancy stages. This r...

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Detalles Bibliográficos
Autores principales: Ramos, Inês Raquel Martins, Malkin, Alison, Lyng, Fiona Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477184/
https://www.ncbi.nlm.nih.gov/pubmed/26180802
http://dx.doi.org/10.1155/2015/561242
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author Ramos, Inês Raquel Martins
Malkin, Alison
Lyng, Fiona Mary
author_facet Ramos, Inês Raquel Martins
Malkin, Alison
Lyng, Fiona Mary
author_sort Ramos, Inês Raquel Martins
collection PubMed
description Raman spectroscopy provides a unique biochemical fingerprint capable of identifying and characterizing the structure of molecules, cells, and tissues. In cervical cancer, it is acknowledged as a promising biochemical tool due to its ability to detect premalignancy and early malignancy stages. This review summarizes the key research in the area and the evidence compiled is very encouraging for ongoing and further research. In addition to the diagnostic potential, promising results for HPV detection and monitoring treatment response suggest more than just a diagnosis prospective. A greater body of evidence is however necessary before Raman spectroscopy is fully validated for clinical use and larger comprehensive studies are required to fully establish the role of Raman spectroscopy in the molecular diagnostics of cervical cancer.
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spelling pubmed-44771842015-07-15 Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer Ramos, Inês Raquel Martins Malkin, Alison Lyng, Fiona Mary Biomed Res Int Review Article Raman spectroscopy provides a unique biochemical fingerprint capable of identifying and characterizing the structure of molecules, cells, and tissues. In cervical cancer, it is acknowledged as a promising biochemical tool due to its ability to detect premalignancy and early malignancy stages. This review summarizes the key research in the area and the evidence compiled is very encouraging for ongoing and further research. In addition to the diagnostic potential, promising results for HPV detection and monitoring treatment response suggest more than just a diagnosis prospective. A greater body of evidence is however necessary before Raman spectroscopy is fully validated for clinical use and larger comprehensive studies are required to fully establish the role of Raman spectroscopy in the molecular diagnostics of cervical cancer. Hindawi Publishing Corporation 2015 2015-06-09 /pmc/articles/PMC4477184/ /pubmed/26180802 http://dx.doi.org/10.1155/2015/561242 Text en Copyright © 2015 Inês Raquel Martins Ramos et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ramos, Inês Raquel Martins
Malkin, Alison
Lyng, Fiona Mary
Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer
title Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer
title_full Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer
title_fullStr Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer
title_full_unstemmed Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer
title_short Current Advances in the Application of Raman Spectroscopy for Molecular Diagnosis of Cervical Cancer
title_sort current advances in the application of raman spectroscopy for molecular diagnosis of cervical cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477184/
https://www.ncbi.nlm.nih.gov/pubmed/26180802
http://dx.doi.org/10.1155/2015/561242
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