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Resveratrol: A Focus on Several Neurodegenerative Diseases

Molecules of the plant world are proving their effectiveness in countering, slowing down, and regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene structure has been proven to be a universal panacea, especially for a wide range of neurodegenerative diseases....

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Autores principales: Tellone, Ester, Galtieri, Antonio, Russo, Annamaria, Giardina, Bruno, Ficarra, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477222/
https://www.ncbi.nlm.nih.gov/pubmed/26180587
http://dx.doi.org/10.1155/2015/392169
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author Tellone, Ester
Galtieri, Antonio
Russo, Annamaria
Giardina, Bruno
Ficarra, Silvana
author_facet Tellone, Ester
Galtieri, Antonio
Russo, Annamaria
Giardina, Bruno
Ficarra, Silvana
author_sort Tellone, Ester
collection PubMed
description Molecules of the plant world are proving their effectiveness in countering, slowing down, and regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene structure has been proven to be a universal panacea, especially for a wide range of neurodegenerative diseases. This paper evaluates (in vivo and in vitro) the various molecular targets of this peculiar polyphenol and its ability to effectively counter several neurodegenerative disorders such as Parkinson's, Alzheimer's, and Huntington's diseases and amyotrophic lateral sclerosis. What emerges is that, in the deep heterogeneity of the pathologies evaluated, resveratrol through a convergence on the protein targets is able to give therapeutic responses in neuronal cells deeply diversified not only in morphological structure but especially in their function performed in the anatomical district to which they belong.
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spelling pubmed-44772222015-07-15 Resveratrol: A Focus on Several Neurodegenerative Diseases Tellone, Ester Galtieri, Antonio Russo, Annamaria Giardina, Bruno Ficarra, Silvana Oxid Med Cell Longev Review Article Molecules of the plant world are proving their effectiveness in countering, slowing down, and regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene structure has been proven to be a universal panacea, especially for a wide range of neurodegenerative diseases. This paper evaluates (in vivo and in vitro) the various molecular targets of this peculiar polyphenol and its ability to effectively counter several neurodegenerative disorders such as Parkinson's, Alzheimer's, and Huntington's diseases and amyotrophic lateral sclerosis. What emerges is that, in the deep heterogeneity of the pathologies evaluated, resveratrol through a convergence on the protein targets is able to give therapeutic responses in neuronal cells deeply diversified not only in morphological structure but especially in their function performed in the anatomical district to which they belong. Hindawi Publishing Corporation 2015 2015-06-09 /pmc/articles/PMC4477222/ /pubmed/26180587 http://dx.doi.org/10.1155/2015/392169 Text en Copyright © 2015 Ester Tellone et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Tellone, Ester
Galtieri, Antonio
Russo, Annamaria
Giardina, Bruno
Ficarra, Silvana
Resveratrol: A Focus on Several Neurodegenerative Diseases
title Resveratrol: A Focus on Several Neurodegenerative Diseases
title_full Resveratrol: A Focus on Several Neurodegenerative Diseases
title_fullStr Resveratrol: A Focus on Several Neurodegenerative Diseases
title_full_unstemmed Resveratrol: A Focus on Several Neurodegenerative Diseases
title_short Resveratrol: A Focus on Several Neurodegenerative Diseases
title_sort resveratrol: a focus on several neurodegenerative diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477222/
https://www.ncbi.nlm.nih.gov/pubmed/26180587
http://dx.doi.org/10.1155/2015/392169
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AT giardinabruno resveratrolafocusonseveralneurodegenerativediseases
AT ficarrasilvana resveratrolafocusonseveralneurodegenerativediseases