Cargando…
Ionizing air affects influenza virus infectivity and prevents airborne-transmission
By the use of a modified ionizer device we describe effective prevention of airborne transmitted influenza A (strain Panama 99) virus infection between animals and inactivation of virus (>97%). Active ionizer prevented 100% (4/4) of guinea pigs from infection. Moreover, the device effectively cap...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477231/ https://www.ncbi.nlm.nih.gov/pubmed/26101102 http://dx.doi.org/10.1038/srep11431 |
_version_ | 1782377719300882432 |
---|---|
author | Hagbom, Marie Nordgren, Johan Nybom, Rolf Hedlund, Kjell-Olof Wigzell, Hans Svensson, Lennart |
author_facet | Hagbom, Marie Nordgren, Johan Nybom, Rolf Hedlund, Kjell-Olof Wigzell, Hans Svensson, Lennart |
author_sort | Hagbom, Marie |
collection | PubMed |
description | By the use of a modified ionizer device we describe effective prevention of airborne transmitted influenza A (strain Panama 99) virus infection between animals and inactivation of virus (>97%). Active ionizer prevented 100% (4/4) of guinea pigs from infection. Moreover, the device effectively captured airborne transmitted calicivirus, rotavirus and influenza virus, with recovery rates up to 21% after 40 min in a 19 m(3) room. The ionizer generates negative ions, rendering airborne particles/aerosol droplets negatively charged and electrostatically attracts them to a positively charged collector plate. Trapped viruses are then identified by reverse transcription quantitative real-time PCR. The device enables unique possibilities for rapid and simple removal of virus from air and offers possibilities to simultaneously identify and prevent airborne transmission of viruses. |
format | Online Article Text |
id | pubmed-4477231 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-44772312015-06-24 Ionizing air affects influenza virus infectivity and prevents airborne-transmission Hagbom, Marie Nordgren, Johan Nybom, Rolf Hedlund, Kjell-Olof Wigzell, Hans Svensson, Lennart Sci Rep Article By the use of a modified ionizer device we describe effective prevention of airborne transmitted influenza A (strain Panama 99) virus infection between animals and inactivation of virus (>97%). Active ionizer prevented 100% (4/4) of guinea pigs from infection. Moreover, the device effectively captured airborne transmitted calicivirus, rotavirus and influenza virus, with recovery rates up to 21% after 40 min in a 19 m(3) room. The ionizer generates negative ions, rendering airborne particles/aerosol droplets negatively charged and electrostatically attracts them to a positively charged collector plate. Trapped viruses are then identified by reverse transcription quantitative real-time PCR. The device enables unique possibilities for rapid and simple removal of virus from air and offers possibilities to simultaneously identify and prevent airborne transmission of viruses. Nature Publishing Group 2015-06-23 /pmc/articles/PMC4477231/ /pubmed/26101102 http://dx.doi.org/10.1038/srep11431 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Hagbom, Marie Nordgren, Johan Nybom, Rolf Hedlund, Kjell-Olof Wigzell, Hans Svensson, Lennart Ionizing air affects influenza virus infectivity and prevents airborne-transmission |
title | Ionizing air affects influenza virus infectivity and prevents airborne-transmission |
title_full | Ionizing air affects influenza virus infectivity and prevents airborne-transmission |
title_fullStr | Ionizing air affects influenza virus infectivity and prevents airborne-transmission |
title_full_unstemmed | Ionizing air affects influenza virus infectivity and prevents airborne-transmission |
title_short | Ionizing air affects influenza virus infectivity and prevents airborne-transmission |
title_sort | ionizing air affects influenza virus infectivity and prevents airborne-transmission |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477231/ https://www.ncbi.nlm.nih.gov/pubmed/26101102 http://dx.doi.org/10.1038/srep11431 |
work_keys_str_mv | AT hagbommarie ionizingairaffectsinfluenzavirusinfectivityandpreventsairbornetransmission AT nordgrenjohan ionizingairaffectsinfluenzavirusinfectivityandpreventsairbornetransmission AT nybomrolf ionizingairaffectsinfluenzavirusinfectivityandpreventsairbornetransmission AT hedlundkjellolof ionizingairaffectsinfluenzavirusinfectivityandpreventsairbornetransmission AT wigzellhans ionizingairaffectsinfluenzavirusinfectivityandpreventsairbornetransmission AT svenssonlennart ionizingairaffectsinfluenzavirusinfectivityandpreventsairbornetransmission |