Protective Pleiotropic Effect of Flavonoids on NAD(+) Levels in Endothelial Cells Exposed to High Glucose

NAD(+) is important for oxidative metabolism by serving as an electron transporter. Hyperglycemia decreases NAD(+) levels by activation of the polyol pathway and by overactivation of poly(ADP-ribose)-polymerase (PARP). We examined the protective role of three structurally related flavonoids (rutin,...

Descripción completa

Detalles Bibliográficos
Autores principales: Boesten, Daniëlle M. P. H. J., von Ungern-Sternberg, Saskia N. I., den Hartog, Gertjan J. M., Bast, Aalt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477254/
https://www.ncbi.nlm.nih.gov/pubmed/26180598
http://dx.doi.org/10.1155/2015/894597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477254/
https://www.ncbi.nlm.nih.gov/pubmed/26180598
http://dx.doi.org/10.1155/2015/894597

Ejemplares similares