Cargando…

Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes

Single nucleotide polymorphism (SNP) rs10911021 at the glutamate-ammonia ligase (GLUL) locus has been associated with an increased risk of coronary heart disease in individuals with type 2 diabetes. The effect of this SNP on mortality was investigated among 1,242 white subjects with type 2 diabetes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prudente, Sabrina, Shah, Hetal, Bailetti, Diego, Pezzolesi, Marcus, Buranasupkajorn, Patinut, Mercuri, Luana, Mendonca, Christine, De Cosmo, Salvatore, Niewczas, Monika, Trischitta, Vincenzo, Doria, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2015
Materias:	Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477355/ https://www.ncbi.nlm.nih.gov/pubmed/25677913 http://dx.doi.org/10.2337/db14-1653

Ejemplares similares

PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid
por: Morieri, Mario Luca, et al.
Publicado: (2020)

Prospective Association of GLUL rs10911021 With Cardiovascular Morbidity and Mortality Among Individuals With Type 2 Diabetes: The Look AHEAD Study
Publicado: (2016)

Circulating metabolites improve the prediction of renal impairment in patients with type 2 diabetes
por: Trischitta, Vincenzo, et al.
Publicado: (2023)

Metabolomic Changes in Serum of Children with Different Clinical Diagnoses of Malnutrition(1)(2)(3)
por: Di Giovanni, Valeria, et al.
Publicado: (2016)

Metabolic Footprinting of Fermented Milk Consumption in Serum of Healthy Men
por: Pimentel, Grégory, et al.
Publicado: (2018)

The Plasma Proteome Is Associated with Anthropometric Status of Undernourished Nepalese School-Aged Children(1)(2)(3)
por: Lee, Sun Eun, et al.
Publicado: (2017)

Identification of Milk and Cheese Intake Biomarkers in Healthy Adults Reveals High Interindividual Variability of Lewis System–Related Oligosaccharides
por: Pimentel, Grégory, et al.
Publicado: (2020)

Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish
por: Axton, Elizabeth R, et al.
Publicado: (2019)

Personalized Profiling Reveals Donor- and Lactation-Specific Trends in the Human Milk Proteome and Peptidome
por: Zhu, Jing, et al.
Publicado: (2021)

Urine Metabolite Profiles and Nutrient Intake Based on 4-Day Weighed Food Diary in Habitual Vegans, Vegetarians, and Omnivores
por: Lindqvist, Helen M, et al.
Publicado: (2020)

DHA Supplementation Attenuates Inflammation-Associated Gene Expression in the Mammary Gland of Lactating Mothers Who Deliver Preterm
por: Adams, Joselyn M, et al.
Publicado: (2022)

Plasma MicroRNA Signature of Alcohol Consumption: The Rotterdam Study
por: Karabegović, Irma, et al.
Publicado: (2022)

New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins
por: Roshandel, Delnaz, et al.
Publicado: (2016)

A Genome-Wide Association Study in American Indians Implicates DNER as a Susceptibility Locus for Type 2 Diabetes
por: Hanson, Robert L., et al.
Publicado: (2014)

Genome-Wide Association Study for Type 2 Diabetes in Indians Identifies a New Susceptibility Locus at 2q21
por: Tabassum, Rubina, et al.
Publicado: (2013)

Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets
por: Travers, Mary E., et al.
Publicado: (2013)

Genetic Predisposition to Dyslipidemia and Type 2 Diabetes Risk in Two Prospective Cohorts
por: Qi, Qibin, et al.
Publicado: (2012)

Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes
por: Forgetta, Vincenzo, et al.
Publicado: (2020)

A Fecal Metabolite Signature of Impaired Fasting Glucose: Results From Two Independent Population-Based Cohorts
por: Nogal, Ana, et al.
Publicado: (2023)

Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation
por: Warren, Liling L., et al.
Publicado: (2012)

No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels
por: Scott, Robert A., et al.
Publicado: (2012)

Peripheral Blood Monocyte Gene Expression Profile Clinically Stratifies Patients With Recent-Onset Type 1 Diabetes
por: Irvine, Katharine M., et al.
Publicado: (2012)

Placental Adiponectin Gene DNA Methylation Levels Are Associated With Mothers’ Blood Glucose Concentration
por: Bouchard, Luigi, et al.
Publicado: (2012)

Consistent Directions of Effect for Established Type 2 Diabetes Risk Variants Across Populations: The Population Architecture using Genomics and Epidemiology (PAGE) Consortium
por: Haiman, Christopher A., et al.
Publicado: (2012)

Hyperglycemia and a Common Variant of GCKR Are Associated With the Levels of Eight Amino Acids in 9,369 Finnish Men
por: Stančáková, Alena, et al.
Publicado: (2012)

A Gene-Family Analysis of 61 Genetic Variants in the Nicotinic Acetylcholine Receptor Genes for Insulin Resistance and Type 2 Diabetes in American Indians
por: Yang, Jingyun, et al.
Publicado: (2012)

MicroRNA Dysregulation in Diabetic Ischemic Heart Failure Patients
por: Greco, Simona, et al.
Publicado: (2012)

Effect of the PTPN22 and INS Risk Genotypes on the Progression to Clinical Type 1 Diabetes After the Initiation of β-Cell Autoimmunity
por: Lempainen, Johanna, et al.
Publicado: (2012)

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression
por: Bergholdt, Regine, et al.
Publicado: (2012)

Global DNA Methylation Is Associated With Insulin Resistance: A Monozygotic Twin Study
por: Zhao, Jinying, et al.
Publicado: (2012)

Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk
por: Marquez, Marcel, et al.
Publicado: (2012)

A Genome-Wide Association Study of Gestational Diabetes Mellitus in Korean Women
por: Kwak, Soo Heon, et al.
Publicado: (2012)

Effects of Non-HLA Gene Polymorphisms on Development of Islet Autoimmunity and Type 1 Diabetes in a Population With High-Risk HLA-DR,DQ Genotypes
por: Steck, Andrea K., et al.
Publicado: (2012)

The ATP-Sensitive K(+) Channel ABCC8 S1369A Type 2 Diabetes Risk Variant Increases MgATPase Activity
por: Fatehi, Mohammad, et al.
Publicado: (2012)

Relative Expression of a Dominant Mutated ABCC8 Allele Determines the Clinical Manifestation of Congenital Hyperinsulinism
por: Shemer, Ruth, et al.
Publicado: (2012)

Greater Impact of Melanocortin-4 Receptor Deficiency on Rates of Growth and Risk of Type 2 Diabetes During Childhood Compared With Adulthood in Pima Indians
por: Thearle, Marie S., et al.
Publicado: (2012)

Mitochondrial DNA Coding and Control Region Variants as Genetic Risk Factors for Type 2 Diabetes
por: Liou, Chia-Wei, et al.
Publicado: (2012)

Impact of Common Variation in Bone-Related Genes on Type 2 Diabetes and Related Traits
por: Billings, Liana K., et al.
Publicado: (2012)

Changing Metabolic Signatures of Amino Acids and Lipids During the Prediabetic Period in a Pig Model With Impaired Incretin Function and Reduced β-Cell Mass
por: Renner, Simone, et al.
Publicado: (2012)

Association Testing of Previously Reported Variants in a Large Case-Control Meta-analysis of Diabetic Nephropathy
por: Williams, Winfred W., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ta3gerlbbgebvavqlb0mc6fi91