Adenylyl Cyclase Type 5 Deficiency Protects Against Diet-Induced Obesity and Insulin Resistance

Adenylyl cyclase type 5 knockout (AC5KO) mice have increased longevity and share a similar phenotype with calorie-restricted wild-type (WT) mice. To determine the in vivo metabolic properties of AC5 deficiency, we compared the effects of standard diet (SD) and high-fat diet (HFD) on obesity, energy...

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Detalles Bibliográficos
Autores principales: Ho, David, Zhao, Xin, Yan, Lin, Yuan, Chujun, Zong, Haihong, Vatner, Dorothy E., Pessin, Jeffery E., Vatner, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477357/
https://www.ncbi.nlm.nih.gov/pubmed/25732192
http://dx.doi.org/10.2337/db14-0494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477357/
https://www.ncbi.nlm.nih.gov/pubmed/25732192
http://dx.doi.org/10.2337/db14-0494

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