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In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs
Membrane receptor-sensed input signals affect and modulate intracellular protein-protein interactions (PPIs). Consequent changes occur to the compositions of protein complexes, protein localization and intermolecular binding affinities. Alterations of compartmentalized PPIs emanating from certain de...
Autores principales: | Röck, Ruth, Bachmann, Verena, Bhang, Hyo-eun C, Malleshaiah, Mohan, Raffeiner, Philipp, Mayrhofer, Johanna E, Tschaikner, Philipp M, Bister, Klaus, Aanstad, Pia, Pomper, Martin G, Michnick, Stephen W, Stefan, Eduard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477410/ https://www.ncbi.nlm.nih.gov/pubmed/26099953 http://dx.doi.org/10.1038/srep11133 |
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