Cargando…

Structural modeling of the N-terminal signal–receiving domain of IκBα

The transcription factor nuclear factor-κB (NF-κB) exerts essential roles in many biological processes including cell growth, apoptosis and innate and adaptive immunity. The NF-κB inhibitor (IκBα) retains NF-κB in the cytoplasm and thus inhibits nuclear localization of NF-κB and its association with...

Descripción completa

Detalles Bibliográficos
Autores principales: Yazdi, Samira, Durdagi, Serdar, Naumann, Michael, Stein, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477481/
https://www.ncbi.nlm.nih.gov/pubmed/26157801
http://dx.doi.org/10.3389/fmolb.2015.00032