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The prognostic significance of CXCL1 hypersecretion by human colorectal cancer epithelia and myofibroblasts

BACKGROUND: Clinical therapy for metastatic colorectal cancer (CRC) remains limited, especially when the tumor harbors a KRAS mutation. This study aimed to identify prognostic biomarkers in CRC that are accessible for therapeutic inhibition. METHODS: Conditioned media from human CRC epithelial cells...

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Detalles Bibliográficos
Autores principales:	le Rolle, Anne-France, Chiu, Thang K, Fara, Michael, Shia, Jinru, Zeng, Zhaoshi, Weiser, Martin R, Paty, Philip B, Chiu, Vi K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477596/ https://www.ncbi.nlm.nih.gov/pubmed/26104296 http://dx.doi.org/10.1186/s12967-015-0555-4

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