Mesenchymal stromal cells of osteosarcoma patients do not show evidence of neoplastic changes during long-term culture

BACKGROUND: In vitro expanded mesenchymal stromal cells (MSCs) are increasingly used as experimental cellular therapy. However, there have been concerns regarding the safety of their use, particularly with regard to possible oncogenic transformation. MSCs are the hypothesized precursor cells of high...

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Detalles Bibliográficos
Autores principales: Buddingh, Emilie P, Ruslan, S Eriaty N, Reijnders, Christianne M A, Szuhai, Karoly, Kuijjer, Marieke L, Roelofs, Helene, Hogendoorn, Pancras C W, Maarten Egeler, R, Cleton-Jansen, Anne-Marie, Lankester, Arjan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477606/
https://www.ncbi.nlm.nih.gov/pubmed/26106474
http://dx.doi.org/10.1186/s13569-015-0031-1

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