Development of a high-resolution NGS-based HLA-typing and analysis pipeline

The human leukocyte antigen (HLA) complex contains the most polymorphic genes in the human genome. The classical HLA class I and II genes define the specificity of adaptive immune responses. Genetic variation at the HLA genes is associated with susceptibility to autoimmune and infectious diseases an...

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Detalles Bibliográficos
Autores principales: Wittig, Michael, Anmarkrud, Jarl A., Kässens, Jan C., Koch, Simon, Forster, Michael, Ellinghaus, Eva, Hov, Johannes R., Sauer, Sascha, Schimmler, Manfred, Ziemann, Malte, Görg, Siegfried, Jacob, Frank, Karlsen, Tom H., Franke, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477639/
https://www.ncbi.nlm.nih.gov/pubmed/25753671
http://dx.doi.org/10.1093/nar/gkv184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477639/
https://www.ncbi.nlm.nih.gov/pubmed/25753671
http://dx.doi.org/10.1093/nar/gkv184

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