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Development of a high-resolution NGS-based HLA-typing and analysis pipeline
The human leukocyte antigen (HLA) complex contains the most polymorphic genes in the human genome. The classical HLA class I and II genes define the specificity of adaptive immune responses. Genetic variation at the HLA genes is associated with susceptibility to autoimmune and infectious diseases an...
Autores principales: | Wittig, Michael, Anmarkrud, Jarl A., Kässens, Jan C., Koch, Simon, Forster, Michael, Ellinghaus, Eva, Hov, Johannes R., Sauer, Sascha, Schimmler, Manfred, Ziemann, Malte, Görg, Siegfried, Jacob, Frank, Karlsen, Tom H., Franke, Andre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477639/ https://www.ncbi.nlm.nih.gov/pubmed/25753671 http://dx.doi.org/10.1093/nar/gkv184 |
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